Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
DR. JAKOB USEMANN, M.D. Ph.D.
Resident Physician, Postdoctoral Research Fellow
Diego Manuel Baur
Postdoc
Former Group Members
Noemi Künstle
PhD Candidate
PROJECTS
>Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Jiafa Zeng
PhD Candidate
Amanda Gisler, PhD
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System
Kim Fabienne Arnold, PhD
Human breath analysis may support the existence of individual metabolic phenotypes
AUTHORS: P Martinez-Lozano Sinues, M Kohler, R ZenobiJOURNAL INFO: PloS one 8 (4), e59909YEAR: 2013LINK https://erj.ersjournals.com/content/42/Suppl_57/P1270.short
Differential mobility analysis-mass spectrometry coupled to XCMS algorithm as a novel analytical platform for metabolic profiling
AUTHORS: P Martínez-Lozano, E Criado, G Vidal, S Cristoni, F Franzoso, M Piatti, ...JOURNAL INFO: Metabolomics 9 (1), 30-43YEAR: 2013LINK https://link.springer.com/article/10.1007/s11306-011-0319-y
Ion mobility spectrometry coupled to laser-induced fluorescence
AUTHORS: V Frankevich, P Martinez-Lozano Sinues, K Barylyuk, R ZenobiJOURNAL INFO: Analytical chemistry 85 (1), 39-43YEAR: 2013LINK https://pubs.acs.org/doi/pdf/10.1021/ac303137e
Monitoring diurnal changes in exhaled human breath
AUTHORS: PML Sinues, M Kohler, R ZenobiJOURNAL INFO: Analytical chemistry 85 (1), 369-373YEAR: 2013LINK https://pubs.acs.org/doi/pdf/10.1021/ac3029097
Mass spectrometry fingerprinting coupled to National Institute of Standards and Technology Mass Spectral search algorithm for pattern recognition
AUTHORS: PML Sinues, RM Alonso-Salces, L Zingaro, A Finiguerra, MV Holland, ...JOURNAL INFO: Analytica chimica acta 755, 28-36YEAR: 2012LINK https://www.sciencedirect.com/science/article/pii/S0003267012014894
Mechanistic study on the ionization of trace gases by an electrospray plume
AUTHORS: PML Sinues, E Criado, G VidalJOURNAL INFO: International Journal of Mass Spectrometry 313, 21-29YEAR: 2012LINK https://www.sciencedirect.com/science/article/pii/S1387380611004969
On-line detection of human skin vapors
AUTHORS: P Martínez-Lozano, JF de la MoraJOURNAL INFO: Journal of the American Society for Mass Spectrometry 20 (6), 1060-1063YEAR: 2011LINK https://pubs.acs.org/doi/pdf/10.1016/j.jasms.2009.01.012
Influence of seasonal factors on the atmospheric particle number concentration and size distribution in Madrid
AUTHORS: FJ Gómez-Moreno, M Pujadas, J Plaza, JJ Rodríguez-Maroto, ...JOURNAL INFO: Atmospheric environment 45 (18), 3169-3180YEAR: 2011LINK https://www.sciencedirect.com/science/article/pii/S1352231011001853
Secondary electrospray ionization-mass spectrometry: breath study on a control group
AUTHORS: P Martinez-Lozano, L Zingaro, A Finiguerra, S CristoniJOURNAL INFO: Journal of breath research 5 (1), 016002YEAR: 2011LINK https://iopscience.iop.org/article/10.1088/1752-7155/5/1/016002/pdf
Separation of isomers L-alanine and sarcosine in urine by electrospray ionization and tandem differential mobility analysis-mass spectrometry
AUTHORS: P Martínez-Lozano, J RusJOURNAL INFO: Journal of the American Society for Mass Spectrometry 21 (7), 1129-1132YEAR: 2010LINK https://www.sciencedirect.com/science/article/pii/S1044030510001157
Spin-off company
