Translational Research of Today,
Standard Care of Tomorrow


Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine

Generate HYPOTHESIS

design the experiment

measure

analyze

validate
ONGOING PROJECTS

DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.

THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS

DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM

RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members

Prof. Dr. Pablo Sinues Ph.D.
Head of Translational Medicine Research Group


Mélina Richard
Lead Research Coordinator, Research Associate
+41 61 704 14 11
PROJECTS
> Placebolomics; Breath Metabolomics of Placebo Effects
> Breath Metabolomics of Pain and Stress

Jiafa Zeng
PhD Candidate
PROJECTS

Zhihong Yin
PhD Candidate
PROJECTS

Noemi Künstle
PhD Candidate
PROJECTS
>Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function

DR. JAKOB USEMANN, M.D. Ph.D.
Resident Physician, Postdoctoral Research Fellow


Former Group Members

Mo Awchi
PhD Candidate
PROJECTS

Amanda Gisler, PhD
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System

Kim Fabienne Arnold, PhD
Influence of seasonal factors on the atmospheric particle number concentration and size distribution in Madrid
AUTHORS: FJ Gómez-Moreno, M Pujadas, J Plaza, JJ Rodríguez-Maroto, ...JOURNAL INFO: Atmospheric environment 45 (18), 3169-3180YEAR: 2011LINK https://www.sciencedirect.com/science/article/pii/S1352231011001853
Secondary electrospray ionization-mass spectrometry: breath study on a control group
AUTHORS: P Martinez-Lozano, L Zingaro, A Finiguerra, S CristoniJOURNAL INFO: Journal of breath research 5 (1), 016002YEAR: 2011LINK https://iopscience.iop.org/article/10.1088/1752-7155/5/1/016002/pdf
Separation of isomers L-alanine and sarcosine in urine by electrospray ionization and tandem differential mobility analysis-mass spectrometry
AUTHORS: P Martínez-Lozano, J RusJOURNAL INFO: Journal of the American Society for Mass Spectrometry 21 (7), 1129-1132YEAR: 2010LINK https://www.sciencedirect.com/science/article/pii/S1044030510001157
MALDI-MS-NIST library approach for colorectal cancer diagnosis
AUTHORS: S Cristoni, L Molin, A Lai, LR Bernardi, S Pucciarelli, M Agostini, C Bedin, ...JOURNAL INFO: Rapid communications in mass spectrometry: RCM 23 (17), 2839-2845YEAR: 2009LINK...
Secondary electrospray ionization (SESI) of ambient vapors for explosive detection at concentrations below parts per trillion
AUTHORS: P Martínez-Lozano, J Rus, GF de la Mora, M Hernández, JF de la MoraJOURNAL INFO: Journal of the American Society for Mass Spectrometry 20 (2), 287-294YEAR: 2009LINK https://www.sciencedirect.com/science/article/pii/S0021850209000135
Direct analysis of fatty acid vapors in breath by electrospray ionization and atmospheric pressure ionization-mass spectrometry
AUTHORS: P Martinez-Lozano, F de la Mora JJOURNAL INFO: Anal Chem 80, 8210-8215YEAR: 2008LINK https://pubs.acs.org/doi/full/10.1021/ac801185e
Particle Measurement Programme (PMP) Heavy-Duty (HD) Inter-laboratory Exercise Validation exercise tests at JRC (Phase A: Feb’08 and Phase B: June’08)
AUTHORS: B Giechaskiel, P Martinez-Lozano, S Alessandrini, F Forni, F Montigny, ...JOURNAL INFO: YEAR: 2008LINK https://publications.jrc.ec.europa.eu/repository/bitstream/JRC47083/reqno_jrc47083_pmp_hd_jrc_validation[1].pdf
Electrospray ionization of volatiles in breath
AUTHORS: P Martínez-Lozano, JF de La MoraJOURNAL INFO: International Journal of Mass Spectrometry 265 (1), 68-72YEAR: 2007LINK https://www.sciencedirect.com/science/article/pii/S1387380607002254
Experimental tests of a nano-DMA with no voltage change between aerosol inlet and outlet slits
AUTHORS: P Martinez-Lozano, M Labowsky, JF de la MoraJOURNAL INFO: Journal of aerosol science 37 (11), 1629-1642YEAR: 2006LINK https://www.sciencedirect.com/science/article/pii/S0021850206000292
Resolution improvements of a nano-DMA operating transonically
AUTHORS: P Martínez-Lozano, JF de la MoraJOURNAL INFO: Journal of Aerosol Science 37 (4), 500-512YEAR: 2006LINK https://www.sciencedirect.com/science/article/pii/S0021850205000972
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