Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
Malena Maira Gwerder, MD
PhD Candidate
Diego Manuel Baur
Postdoc
Nachelli Malpica
Master student
PROJECTS
Development of Standard Operating Procedures for Reproducible Offline Breath Analysis
Former Group Members
Noemi Künstle, MD, PhD
PhD Candidate
PROJECTS
>Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Jiafa Zeng, PhD
PhD Candidate
Amanda Gisler, PhD
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System
Kim Fabienne Arnold, PhD
Real-time detection of chemical warfare agent simulants in forensic samples using active capillary plasma ionization with benchtop and field-deployable mass spectrometers
AUTHORS: M Dumlao, PML Sinues, M Nudnova, R ZenobiJOURNAL INFO: Analytical Methods 6 (11), 3604-3609YEAR: 2014LINK https://pubs.rsc.org/en/content/articlehtml/2014/ay/c4ay00303a
Breath analysis in real time by mass spectrometry in chronic obstructive pulmonary disease
AUTHORS: PML Sinues, L Meier, C Berchtold, M Ivanov, N Sievi, G Camen, M Kohler, ...JOURNAL INFO: Respiration 87 (4), 301-310YEAR: 2014LINK https://www.karger.com/Article/FullText/357785
Journal of Breath Research
AUTHORS: JD Pleil, PML Sinues, E Landoni, R Miceli, VF Dibari, M Dugo, R Agresti, ...JOURNAL INFO: YEAR: 2013LINK https://iopscience.iop.org/article/10.1088/1752-7155/7/4/040201/pdf
Human breath analysis supports the existence of individual phenotypes
AUTHORS: PML Sinues, R Zenobi, M KohlerJOURNAL INFO: European Respiratory Journal 42 (Suppl 57)YEAR: 2013LINK https://erj.ersjournals.com/content/42/Suppl_57/P1270.short
Analysis of the exhalome: a diagnostic tool of the future
AUTHORS: PML Sinues, R Zenobi, M KohlerJOURNAL INFO: Chest 144 (3), 746-749YEAR: 2013LINK https://www.sciencedirect.com/science/article/pii/S0012369213605899
P280 Human Breath Analysis Supports the Existence of Individual Phenotypes
AUTHORS: P Sinues, R Zenobi, M KohlerJOURNAL INFO: Respiration 85 (6)YEAR: 2013LINK https://erj.ersjournals.com/content/42/Suppl_57/P1270
Human breath analysis may support the existence of individual metabolic phenotypes
AUTHORS: P Martinez-Lozano Sinues, M Kohler, R ZenobiJOURNAL INFO: PloS one 8 (4), e59909YEAR: 2013LINK https://erj.ersjournals.com/content/42/Suppl_57/P1270.short
Differential mobility analysis-mass spectrometry coupled to XCMS algorithm as a novel analytical platform for metabolic profiling
AUTHORS: P Martínez-Lozano, E Criado, G Vidal, S Cristoni, F Franzoso, M Piatti, ...JOURNAL INFO: Metabolomics 9 (1), 30-43YEAR: 2013LINK https://link.springer.com/article/10.1007/s11306-011-0319-y
Ion mobility spectrometry coupled to laser-induced fluorescence
AUTHORS: V Frankevich, P Martinez-Lozano Sinues, K Barylyuk, R ZenobiJOURNAL INFO: Analytical chemistry 85 (1), 39-43YEAR: 2013LINK https://pubs.acs.org/doi/pdf/10.1021/ac303137e
Monitoring diurnal changes in exhaled human breath
AUTHORS: PML Sinues, M Kohler, R ZenobiJOURNAL INFO: Analytical chemistry 85 (1), 369-373YEAR: 2013LINK https://pubs.acs.org/doi/pdf/10.1021/ac3029097
Spin-off company
