Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine

Generate HYPOTHESIS

design the experiment

measure

analyze

validate
ONGOING PROJECTS

DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.

THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS

DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM

RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members



Group Members

Zhihong Yin
PhD Candidate





Former Group Members

Dr. Nachelli Malpica
Former Master Student
PROJECTS
> Development of Standard Operating Procedures for Reproducible Offline Breath Analysis

Dr. Malena Maira Gwerder, MD
Former PhD Candidate
PROJECTS
> Bern Basel Infant Lung Development (BILD) cohort
NEXT
> Assistant Pediatric Doctor at UKBB

Dr. Mo Awchi
Former PhD Candidate
PROJECTS
> Therapeutic Drug Monitoring Guided by Breath Analysis
NEXT
> Senior Operational Specialist at Lonza

Isabel Gonzalez
Former Lead Study Nurse

Dr. Diego Manuel Baur
Former Postdoctoral Researcher

Moor de Waal
Former Student Assistant

Dr. Amanda Gisler
Former PhD Student
PROJECTS
> Standardizing Real-Time Breath AnalysisÂ
> Impact of Air Pollution on the Respiratory System
NEXT
> Management Board Member, LUSTAT Statistics

Fabienne Decrue
Former Responsible Pediatric Doctor
PROJECTS
> Standardisation of Mass Spectrometer Offline Sampling
NEXT
> Pediatric Doctor at UKBB

Dr. Noemi Künstle, MD
Former PhD Candidate
PROJECTS
> Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function

Dr. Jiafa Zeng
Former PhD Candidate

Dr. Kim Fabienne Arnold
Former PhD Student
Monitoring diurnal changes in exhaled human breath
AUTHORS: PML Sinues, M Kohler, R ZenobiJOURNAL INFO: Analytical chemistry 85 (1), 369-373YEAR: 2013LINK https://pubs.acs.org/doi/pdf/10.1021/ac3029097
Mass spectrometry fingerprinting coupled to National Institute of Standards and Technology Mass Spectral search algorithm for pattern recognition
AUTHORS: PML Sinues, RM Alonso-Salces, L Zingaro, A Finiguerra, MV Holland, ...JOURNAL INFO: Analytica chimica acta 755, 28-36YEAR: 2012LINK https://www.sciencedirect.com/science/article/pii/S0003267012014894
Mechanistic study on the ionization of trace gases by an electrospray plume
AUTHORS: PML Sinues, E Criado, G VidalJOURNAL INFO: International Journal of Mass Spectrometry 313, 21-29YEAR: 2012LINK https://www.sciencedirect.com/science/article/pii/S1387380611004969
On-line detection of human skin vapors
AUTHORS: P MartÃnez-Lozano, JF de la MoraJOURNAL INFO: Journal of the American Society for Mass Spectrometry 20 (6), 1060-1063YEAR: 2011LINK https://pubs.acs.org/doi/pdf/10.1016/j.jasms.2009.01.012
Influence of seasonal factors on the atmospheric particle number concentration and size distribution in Madrid
AUTHORS: FJ Gómez-Moreno, M Pujadas, J Plaza, JJ RodrÃguez-Maroto, ...JOURNAL INFO: Atmospheric environment 45 (18), 3169-3180YEAR: 2011LINK https://www.sciencedirect.com/science/article/pii/S1352231011001853
Secondary electrospray ionization-mass spectrometry: breath study on a control group
AUTHORS: P Martinez-Lozano, L Zingaro, A Finiguerra, S CristoniJOURNAL INFO: Journal of breath research 5 (1), 016002YEAR: 2011LINK https://iopscience.iop.org/article/10.1088/1752-7155/5/1/016002/pdf
Separation of isomers L-alanine and sarcosine in urine by electrospray ionization and tandem differential mobility analysis-mass spectrometry
AUTHORS: P MartÃnez-Lozano, J RusJOURNAL INFO: Journal of the American Society for Mass Spectrometry 21 (7), 1129-1132YEAR: 2010LINK https://www.sciencedirect.com/science/article/pii/S1044030510001157
MALDI-MS-NIST library approach for colorectal cancer diagnosis
AUTHORS: S Cristoni, L Molin, A Lai, LR Bernardi, S Pucciarelli, M Agostini, C Bedin, ...JOURNAL INFO: Rapid communications in mass spectrometry: RCM 23 (17), 2839-2845YEAR: 2009LINK...
Secondary electrospray ionization (SESI) of ambient vapors for explosive detection at concentrations below parts per trillion
AUTHORS: P MartÃnez-Lozano, J Rus, GF de la Mora, M Hernández, JF de la MoraJOURNAL INFO: Journal of the American Society for Mass Spectrometry 20 (2), 287-294YEAR: 2009LINK https://www.sciencedirect.com/science/article/pii/S0021850209000135
Direct analysis of fatty acid vapors in breath by electrospray ionization and atmospheric pressure ionization-mass spectrometry
AUTHORS: P Martinez-Lozano, F de la Mora JJOURNAL INFO: Anal Chem 80, 8210-8215YEAR: 2008LINK https://pubs.acs.org/doi/full/10.1021/ac801185e
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