Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
Malena Maira Gwerder, MD
PhD Candidate
Diego Manuel Baur
Postdoc
Nachelli Malpica
Master student
PROJECTS
Development of Standard Operating Procedures for Reproducible Offline Breath Analysis
Former Group Members
Noemi Künstle, MD, PhD
PhD Candidate
PROJECTS
>Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Jiafa Zeng, PhD
PhD Candidate
Amanda Gisler, PhD
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System
Kim Fabienne Arnold, PhD
Comprehensive real-time analysis of the yeast Volatilome
AUTHORS: AT Rioseras, DG Gomez, BE Ebert, LM Blank, AJ Ibáñez, PML SinuesJOURNAL INFO: Scientific reports 7 (1), 1-9YEAR: 2017LINK https://www.nature.com/articles/s41598-017-14554-y
Mass-spectrometric detection of omega-oxidation products of aliphatic fatty acids in exhaled breath
AUTHORS: MT Gaugg, T Bruderer, N Nowak, L Eiffert, P Martinez-Lozano Sinues, ...JOURNAL INFO: Analytical chemistry 89 (19), 10329-10334YEAR: 2017LINK https://pubs.acs.org/doi/full/10.1021/acs.analchem.7b02092
Metabolic effects of inhaled salbutamol determined by exhaled breath analysis
AUTHORS: MT Gaugg, A Engler, Y Nussbaumer-Ochsner, L Bregy, AS Stöberl, ...JOURNAL INFO: Journal of breath research 11 (4), 046004YEAR: 2017LINK https://iopscience.iop.org/article/10.1088/1752-7163/aa7caa/pdf
Real-time exhaled breath analysis identifies altered metabolic signature in cystic fibrosis
AUTHORS: T Gaisl, L Bregy, N Stebler, M Gaugg, T Bruderer, D García-Gómez, ...JOURNAL INFO: Chest 151 (5), A104YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217306530?via%3Dihub
Targeted on-line breath analysis discriminates COPD patients vs. healthy controls and subjects suffering from asthma
AUTHORS: Y Nussbaumer-Ochsner, MT Gaugg, L Bregy, A Engler, SA Sophie, ...JOURNAL INFO: Chest 151 (5), A46-A47YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305937?via%3Dihub
on-line breath analysis with secondary electrospray ionization discriminates between COPD patients with and without frequent exacerbations
AUTHORS: MT Gaugg, Y Nussbaumer-Ochsner, L Bregy, A Engler, N Stebler, ...JOURNAL INFO: Chest 151 (5), A5YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305494?via%3Dihub
Exhaled breath analysis by real-time mass spectrometry in patients with pulmonary fibrosis
AUTHORS: P Sinues, Y Nussbaumer-Ochsner, MT Gaugg, L Bregy, A Engler, ...JOURNAL INFO: Chest 151 (5), A16YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305603?via%3Dihub
Gauging circadian variation in ketamine metabolism by real-time breath analysis
AUTHORS: PML Sinues, M Kohler, SA Brown, R Zenobi, R DallmannJOURNAL INFO: Chemical Communications 53 (14), 2264-2267YEAR: 2017LINK https://pubs.rsc.org/en/content/articlehtml/2017/cc/c6cc09061c
Secondary electrospray ionization proceeds via gas-phase chemical ionization
AUTHORS: AT Rioseras, MT Gaugg, PML SinuesJOURNAL INFO: Analytical Methods 9 (34), 5052-5057YEAR: 2017LINK https://pubs.rsc.org/en/content/articlehtml/2017/ay/c7ay01121k
Real Time Read-Out of Plant Metabolism
AUTHORS: C Barrios-Collado, D García-Gómez, R Zenobi, G Vidal-de-Miguel, ...JOURNAL INFO: CHIMIA International Journal for Chemistry 70 (9), 660-660YEAR: 2016LINK...
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