Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
Former Group Members
Dr. Nachelli Malpica
Master student
PROJECTS
> Development of Standard Operating Procedures for Reproducible Offline Breath Analysis
Dr. Malena Maira Gwerder, MD
PhD Candidate
PROJECTS
> Bern Basel Infant Lung Development (BILD) cohort
NEXT
> Assistant Pediatric Doctor at Universitäts-Kinderspital beider Basel (UKBB) in Basel, Switzerland
Dr. Mo Awchi
PhD Candidate
PROJECTS
> Therapeutic Drug Monitoring Guided by Breath Analysis
NEXT
> Senior Operational Specialist at Lonza in Basel, Switzerland
Isabel Gonzalez
Lead Study Nurse
Moor de Waal
Student Assistant
Dr. Amanda Gisler
PhD Student
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System
NEXT
> Member of the management board at LUSTAT Statistics in Lucerne, Switzerland
Dr. Noemi Künstle, MD
PhD Candidate
PROJECTS
> Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Dr. Kim Fabienne Arnold
PhD Student
PROJECTS
> Rapid Diagnosis of Infectious Respiratory Diseases by Breath Analysis
NEXT
> Medical Affairs Manager at Biomed AG in Dübendorf , Switzerland
Translating secondary electrospray ionization–high-resolution mass spectrometry to the clinical environment
AUTHORS: KD Singh, GV Del Miguel, MT Gaugg, AJ Ibañez, R Zenobi, M Kohler, ...JOURNAL INFO: Journal of breath research 12 (2), 027113YEAR: 2018LINK https://iopscience.iop.org/article/10.1088/1752-7163/aa9ee3/pdf
Real-time mass spectrometric identification of metabolites characteristic of chronic obstructive pulmonary disease in exhaled breath
AUTHORS: L Bregy, Y Nussbaumer-Ochsner, PML Sinues, D García-Gómez, Y Suter, ...JOURNAL INFO: Clinical Mass Spectrometry 7, 29-35YEAR: 2018LINK https://www.sciencedirect.com/science/article/pii/S2376999817300405
Rapid fingerprinting of grape volatile composition using secondary electrospray ionization orbitrap mass spectrometry: A preliminary study of grape ripening
AUTHORS: RR Farrell, J Fahrentrapp, D García-Gómez, PML Sinues, R ZenobiJOURNAL INFO: Food Control 81, 107-112YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0956713517302037
Comprehensive real-time analysis of the yeast Volatilome
AUTHORS: AT Rioseras, DG Gomez, BE Ebert, LM Blank, AJ Ibáñez, PML SinuesJOURNAL INFO: Scientific reports 7 (1), 1-9YEAR: 2017LINK https://www.nature.com/articles/s41598-017-14554-y
Mass-spectrometric detection of omega-oxidation products of aliphatic fatty acids in exhaled breath
AUTHORS: MT Gaugg, T Bruderer, N Nowak, L Eiffert, P Martinez-Lozano Sinues, ...JOURNAL INFO: Analytical chemistry 89 (19), 10329-10334YEAR: 2017LINK https://pubs.acs.org/doi/full/10.1021/acs.analchem.7b02092
Metabolic effects of inhaled salbutamol determined by exhaled breath analysis
AUTHORS: MT Gaugg, A Engler, Y Nussbaumer-Ochsner, L Bregy, AS Stöberl, ...JOURNAL INFO: Journal of breath research 11 (4), 046004YEAR: 2017LINK https://iopscience.iop.org/article/10.1088/1752-7163/aa7caa/pdf
Real-time exhaled breath analysis identifies altered metabolic signature in cystic fibrosis
AUTHORS: T Gaisl, L Bregy, N Stebler, M Gaugg, T Bruderer, D García-Gómez, ...JOURNAL INFO: Chest 151 (5), A104YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217306530?via%3Dihub
Targeted on-line breath analysis discriminates COPD patients vs. healthy controls and subjects suffering from asthma
AUTHORS: Y Nussbaumer-Ochsner, MT Gaugg, L Bregy, A Engler, SA Sophie, ...JOURNAL INFO: Chest 151 (5), A46-A47YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305937?via%3Dihub
on-line breath analysis with secondary electrospray ionization discriminates between COPD patients with and without frequent exacerbations
AUTHORS: MT Gaugg, Y Nussbaumer-Ochsner, L Bregy, A Engler, N Stebler, ...JOURNAL INFO: Chest 151 (5), A5YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305494?via%3Dihub
Exhaled breath analysis by real-time mass spectrometry in patients with pulmonary fibrosis
AUTHORS: P Sinues, Y Nussbaumer-Ochsner, MT Gaugg, L Bregy, A Engler, ...JOURNAL INFO: Chest 151 (5), A16YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305603?via%3Dihub
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