Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
Former Group Members
Dr. Nachelli Malpica
Former Master Student
PROJECTS
> Development of Standard Operating Procedures for Reproducible Offline Breath Analysis
Dr. Malena Maira Gwerder, MD
Former PhD Candidate
PROJECTS
> Bern Basel Infant Lung Development (BILD) cohort
NEXT
> Assistant Pediatric Doctor at UKBB
Dr. Mo Awchi
Former PhD Candidate
PROJECTS
> Therapeutic Drug Monitoring Guided by Breath Analysis
NEXT
> Senior Operational Specialist at Lonza
Isabel Gonzalez
Former Lead Study Nurse
Dr. Diego Manuel Baur
Former Postdoctoral Researcher
Moor de Waal
Former Student Assistant
Dr. Amanda Gisler
Former PhD Student
PROJECTS
> Standardizing Real-Time Breath AnalysisÂ
> Impact of Air Pollution on the Respiratory System
NEXT
> Management Board Member, LUSTAT Statistics
Fabienne Decrue
Former Responsible Pediatric Doctor
PROJECTS
> Standardisation of Mass Spectrometer Offline Sampling
NEXT
> Pediatric Doctor at UKBB
Dr. Noemi Künstle, MD
Former PhD Candidate
PROJECTS
> Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Dr. Jiafa Zeng
Former PhD Candidate
Dr. Kim Fabienne Arnold
Former PhD Student
Rapid fingerprinting of grape volatile composition using secondary electrospray ionization orbitrap mass spectrometry: A preliminary study of grape ripening
AUTHORS: RR Farrell, J Fahrentrapp, D GarcÃa-Gómez, PML Sinues, R ZenobiJOURNAL INFO: Food Control 81, 107-112YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0956713517302037
Comprehensive real-time analysis of the yeast Volatilome
AUTHORS: AT Rioseras, DG Gomez, BE Ebert, LM Blank, AJ Ibáñez, PML SinuesJOURNAL INFO: Scientific reports 7 (1), 1-9YEAR: 2017LINK https://www.nature.com/articles/s41598-017-14554-y
Mass-spectrometric detection of omega-oxidation products of aliphatic fatty acids in exhaled breath
AUTHORS: MT Gaugg, T Bruderer, N Nowak, L Eiffert, P Martinez-Lozano Sinues, ...JOURNAL INFO: Analytical chemistry 89 (19), 10329-10334YEAR: 2017LINK https://pubs.acs.org/doi/full/10.1021/acs.analchem.7b02092
Metabolic effects of inhaled salbutamol determined by exhaled breath analysis
AUTHORS: MT Gaugg, A Engler, Y Nussbaumer-Ochsner, L Bregy, AS Stöberl, ...JOURNAL INFO: Journal of breath research 11 (4), 046004YEAR: 2017LINK https://iopscience.iop.org/article/10.1088/1752-7163/aa7caa/pdf
Real-time exhaled breath analysis identifies altered metabolic signature in cystic fibrosis
AUTHORS: T Gaisl, L Bregy, N Stebler, M Gaugg, T Bruderer, D GarcÃa-Gómez, ...JOURNAL INFO: Chest 151 (5), A104YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217306530?via%3Dihub
Targeted on-line breath analysis discriminates COPD patients vs. healthy controls and subjects suffering from asthma
AUTHORS: Y Nussbaumer-Ochsner, MT Gaugg, L Bregy, A Engler, SA Sophie, ...JOURNAL INFO: Chest 151 (5), A46-A47YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305937?via%3Dihub
on-line breath analysis with secondary electrospray ionization discriminates between COPD patients with and without frequent exacerbations
AUTHORS: MT Gaugg, Y Nussbaumer-Ochsner, L Bregy, A Engler, N Stebler, ...JOURNAL INFO: Chest 151 (5), A5YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305494?via%3Dihub
Exhaled breath analysis by real-time mass spectrometry in patients with pulmonary fibrosis
AUTHORS: P Sinues, Y Nussbaumer-Ochsner, MT Gaugg, L Bregy, A Engler, ...JOURNAL INFO: Chest 151 (5), A16YEAR: 2017LINK https://www.sciencedirect.com/science/article/pii/S0012369217305603?via%3Dihub
Gauging circadian variation in ketamine metabolism by real-time breath analysis
AUTHORS: PML Sinues, M Kohler, SA Brown, R Zenobi, R DallmannJOURNAL INFO: Chemical Communications 53 (14), 2264-2267YEAR: 2017LINK https://pubs.rsc.org/en/content/articlehtml/2017/cc/c6cc09061c
Secondary electrospray ionization proceeds via gas-phase chemical ionization
AUTHORS: AT Rioseras, MT Gaugg, PML SinuesJOURNAL INFO: Analytical Methods 9 (34), 5052-5057YEAR: 2017LINK https://pubs.rsc.org/en/content/articlehtml/2017/ay/c7ay01121k
Spin-off company
