Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
Former Group Members
Dr. Nachelli Malpica
Master student
PROJECTS
> Development of Standard Operating Procedures for Reproducible Offline Breath Analysis
Dr. Malena Maira Gwerder, MD
PhD Candidate
PROJECTS
> Bern Basel Infant Lung Development (BILD) cohort
NEXT
> Assistant Pediatric Doctor at Universitäts-Kinderspital beider Basel (UKBB) in Basel, Switzerland
Dr. Mo Awchi
PhD Candidate
PROJECTS
> Therapeutic Drug Monitoring Guided by Breath Analysis
NEXT
> Senior Operational Specialist at Lonza in Basel, Switzerland
Isabel Gonzalez
Lead Study Nurse
Moor de Waal
Student Assistant
Dr. Amanda Gisler
PhD Student
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System
NEXT
> Member of the management board at LUSTAT Statistics in Lucerne, Switzerland
Dr. Noemi Künstle, MD
PhD Candidate
PROJECTS
> Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Dr. Kim Fabienne Arnold
PhD Student
PROJECTS
> Rapid Diagnosis of Infectious Respiratory Diseases by Breath Analysis
NEXT
> Medical Affairs Manager at Biomed AG in Dübendorf , Switzerland
Gauging circadian variation in ketamine metabolism by real-time breath analysis
AUTHORS: PML Sinues, M Kohler, SA Brown, R Zenobi, R DallmannJOURNAL INFO: Chemical Communications 53 (14), 2264-2267YEAR: 2017LINK https://pubs.rsc.org/en/content/articlehtml/2017/cc/c6cc09061c
Secondary electrospray ionization proceeds via gas-phase chemical ionization
AUTHORS: AT Rioseras, MT Gaugg, PML SinuesJOURNAL INFO: Analytical Methods 9 (34), 5052-5057YEAR: 2017LINK https://pubs.rsc.org/en/content/articlehtml/2017/ay/c7ay01121k
Real Time Read-Out of Plant Metabolism
AUTHORS: C Barrios-Collado, D García-Gómez, R Zenobi, G Vidal-de-Miguel, ...JOURNAL INFO: CHIMIA International Journal for Chemistry 70 (9), 660-660YEAR: 2016LINK...
Real-time determination of slightly volatile amino acids in the exhalome by secondary electrospray ionization. A proof-of-principle study
AUTHORS: T Gaisl, D García-Gómez, L Bregy, A Cremonesi, PML Sinues, M Kohler, ...JOURNAL INFO: European Respiratory Journal 48 (suppl 60)YEAR: 2016LINK https://erj.ersjournals.com/content/48/suppl_60/PA3551
Real-time quantification of amino acids in the Exhalome by secondary electrospray ionization–mass spectrometry: a proof-of-principle study
AUTHORS: D García-Gómez, T Gaisl, L Bregy, A Cremonesi, PML Sinues, M Kohler, ...JOURNAL INFO: Clinical chemistry 62 (9), 1230-1237YEAR: 2016LINK https://academic.oup.com/clinchem/article/62/9/1230/5611979
Noninvasive strategies for breast cancer early detection
AUTHORS: G Trecate, PML Sinues, R OrlandiJOURNAL INFO: Future oncology 12 (11), 1395-1411YEAR: 2016LINK https://www.futuremedicine.com/doi/abs/10.2217/fon-2015-0071
Metabolic Effects of Inhaled Salbutamol Determined by Exhaled Breath Analysis: PP-143
AUTHORS: P Sinues, Y Nussbaumer-Ochsner, L Bregy, A Engler, T Gaisl, M Gaugg, ...JOURNAL INFO: Respiration 91 (5)YEAR: 2016LINK https://iopscience.iop.org/article/10.1088/1752-7163/aa7caa/meta
On-Line Breath Analysis of COPD Patients Reveals Altered Metabolic Signatures between Frequent and Non-Frequent Exacerbators: PP-127
AUTHORS: M Gaugg, Y Nussbaumer-Ochsner, L Bregy, A Engler, N Stebler, T Gaisl, ...JOURNAL INFO: Respiration 91 (5)YEAR: 2016LINK https://journal.chestnet.org/article/S0012-3692(19)30062-5/abstract
Exhaled Breath Analysis Identifies Altered Metabolic Signature in Chronic Obstructive Pulmonary Disease: PP-130
AUTHORS: L Bregy, Y Nussbaumer-Ochsner, D García-Gómez, Y Suter, T Gaisl, ...JOURNAL INFO: Respiration 91 (5), 430-431YEAR: 2016LINK...
Capturing in vivo plant metabolism by real-time analysis of low to high molecular weight volatiles
AUTHORS: C Barrios-Collado, D García-Gómez, R Zenobi, G Vidal-de-Miguel, ...JOURNAL INFO: Analytical chemistry 88 (4), 2406-2412YEAR: 2016LINK https://pubs.acs.org/doi/full/10.1021/acs.analchem.5b04452
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