Translational Research of Today,
Standard Care of Tomorrow
Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine
Generate HYPOTHESIS
design the experiment
measure
analyze
validate
ONGOING PROJECTS
DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.
THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS
DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM
RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members
Core Members
Group Members
Zhihong Yin
PhD Candidate
Malena Maira Gwerder, MD
PhD Candidate
Diego Manuel Baur
Postdoc
Nachelli Malpica
Master student
PROJECTS
Development of Standard Operating Procedures for Reproducible Offline Breath Analysis
Former Group Members
Noemi Künstle, MD, PhD
PhD Candidate
PROJECTS
>Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function
Jiafa Zeng, PhD
PhD Candidate
Amanda Gisler, PhD
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System
Kim Fabienne Arnold, PhD
Real-time determination of slightly volatile amino acids in the exhalome by secondary electrospray ionization. A proof-of-principle study
AUTHORS: T Gaisl, D García-Gómez, L Bregy, A Cremonesi, PML Sinues, M Kohler, ...JOURNAL INFO: European Respiratory Journal 48 (suppl 60)YEAR: 2016LINK https://erj.ersjournals.com/content/48/suppl_60/PA3551
Real-time quantification of amino acids in the Exhalome by secondary electrospray ionization–mass spectrometry: a proof-of-principle study
AUTHORS: D García-Gómez, T Gaisl, L Bregy, A Cremonesi, PML Sinues, M Kohler, ...JOURNAL INFO: Clinical chemistry 62 (9), 1230-1237YEAR: 2016LINK https://academic.oup.com/clinchem/article/62/9/1230/5611979
Noninvasive strategies for breast cancer early detection
AUTHORS: G Trecate, PML Sinues, R OrlandiJOURNAL INFO: Future oncology 12 (11), 1395-1411YEAR: 2016LINK https://www.futuremedicine.com/doi/abs/10.2217/fon-2015-0071
Metabolic Effects of Inhaled Salbutamol Determined by Exhaled Breath Analysis: PP-143
AUTHORS: P Sinues, Y Nussbaumer-Ochsner, L Bregy, A Engler, T Gaisl, M Gaugg, ...JOURNAL INFO: Respiration 91 (5)YEAR: 2016LINK https://iopscience.iop.org/article/10.1088/1752-7163/aa7caa/meta
On-Line Breath Analysis of COPD Patients Reveals Altered Metabolic Signatures between Frequent and Non-Frequent Exacerbators: PP-127
AUTHORS: M Gaugg, Y Nussbaumer-Ochsner, L Bregy, A Engler, N Stebler, T Gaisl, ...JOURNAL INFO: Respiration 91 (5)YEAR: 2016LINK https://journal.chestnet.org/article/S0012-3692(19)30062-5/abstract
Exhaled Breath Analysis Identifies Altered Metabolic Signature in Chronic Obstructive Pulmonary Disease: PP-130
AUTHORS: L Bregy, Y Nussbaumer-Ochsner, D García-Gómez, Y Suter, T Gaisl, ...JOURNAL INFO: Respiration 91 (5), 430-431YEAR: 2016LINK...
Capturing in vivo plant metabolism by real-time analysis of low to high molecular weight volatiles
AUTHORS: C Barrios-Collado, D García-Gómez, R Zenobi, G Vidal-de-Miguel, ...JOURNAL INFO: Analytical chemistry 88 (4), 2406-2412YEAR: 2016LINK https://pubs.acs.org/doi/full/10.1021/acs.analchem.5b04452
Expanding metabolite coverage of real-time breath analysis by coupling a universal secondary electrospray ionization source and high resolution mass spectrometry—a pilot study …
AUTHORS: MT Gaugg, DG Gomez, C Barrios-Collado, G Vidal-de-Miguel, M Kohler, ...JOURNAL INFO: Journal of breath research 10 (1), 016010YEAR: 2016LINK https://iopscience.iop.org/article/10.1088/1752-7155/10/1/016010/pdf
Effects of CPAP therapy withdrawal on exhaled breath pattern in obstructive sleep apnoea
AUTHORS: EI Schwarz, PML Sinues, L Bregy, T Gaisl, DG Gomez, MT Gaugg, Y Suter, ...JOURNAL INFO: Thorax 71 (2), 110-117YEAR: 2016LINK https://thorax.bmj.com/content/thoraxjnl/71/2/110.full.pdf
Numerical modeling and experimental validation of a universal secondary electrospray ionization source for mass spectrometric gas analysis in real-time
AUTHORS: C Barrios-Collado, G Vidal-de-Miguel, PML SinuesJOURNAL INFO: Sensors and Actuators B: Chemical 223, 217-225YEAR: 2016LINK https://www.sciencedirect.com/science/article/pii/S0925400515303804
Spin-off company
