Translational Research of Today,
Standard Care of Tomorrow


Unleashing the Full Potential of Breath Metabolomics to Advance Precision Medicine

Generate HYPOTHESIS

design the experiment

measure

analyze

validate
ONGOING PROJECTS

DEVELOPMENT OF STANDARD OPERATING PROCEDURES FOR REPRODUCIBLE REAL-TIME BREATH ANALYSIS
In this project we develop the necessary procedures to ensure the highest data quality possible, enabling multi-center studies.

THERAPEUTIC DRUG MONITORING GUIDED BY BREATH ANALYSIS

DECIPHERING THE IMPACT OF AIR POLLUTION EXPOSURE FOR THE RESPIRATORY SYSTEM

RAPID DIAGNOSIS OF INFECTIOUS RESPIRATORY DISEASES BY BREATH ANALYSIS
News
Research Group
Members

Prof. Dr. Pablo Sinues Ph.D.
Head of Translational Medicine Research Group


Mélina Richard
Lead Research Coordinator, Research Associate

Kim Fabienne Arnold
PhD Candidate

Amanda Gisler
PhD Candidate
PROJECTS
> Development of Standard Operating Procedures for Reproducible Real-Time Breath Analysis
> Deciphering the Impact of Air Pollution Exposure for the Respiratory System

Jiafa Zeng
PhD Candidate
PROJECTS

Mo Awchi
PhD Candidate
PROJECTS

Noemi Künstle
PhD Candidate
PROJECTS
>Differences in markers of oxidative stress response, autophagy, cellular senescence and remodeling in cord blood in preterm infants compared to term infants and their correlation with air pollution and lung function


DR. JAKOB USEMANN, M.D. Ph.D.
Resident Physician, Postdoctoral Research Fellow

Rapid identification of bacteria in blood cultures by mass-spectrometric analysis of volatiles
AUTHORS: C Ballabio, S Cristoni, G Puccio, M Kohler, MR Sala, P Brambilla, ...JOURNAL INFO: Journal of clinical pathology 67 (8), 743-746YEAR: 2014LINK https://jcp.bmj.com/content/jclinpath/67/8/743.full.pdf
Fingerprinting breast cancer vs. normal mammary cells by mass spectrometric analysis of volatiles
AUTHORS: J He, PML Sinues, M Hollmén, X Li, M Detmar, R ZenobiJOURNAL INFO: Scientific reports 4 (1), 1-6YEAR: 2014LINK https://www.nature.com/articles/srep05196
Rapid Characterization of Oral Bacterial Cultures: P124
AUTHORS: P Sinues, X Li, A Müggler, L Bregy, G Belibasakis, R Zenobi, M Kohler, ...JOURNAL INFO: Respiration 87 (6), 552-553YEAR: 2014LINK...
Determination of Smoking Status by Real-Time Mass Spectrometry: P135
AUTHORS: P Sinues, X Li, N Sievi, R Zenobi, M KohlerJOURNAL INFO: Respiration 87 (6)YEAR: 2014LINK https://www.zora.uzh.ch/id/eprint/131026/1/ZORA131026.pdf
Real-time breath analysis with active capillary plasma ionization-ambient mass spectrometry
AUTHORS: L Bregy, PML Sinues, MM Nudnova, R ZenobiJOURNAL INFO: Journal of breath research 8 (2), 027102YEAR: 2014LINK https://iopscience.iop.org/article/10.1088/1752-7155/8/2/027102/pdf
Mass Spectrometry Research at the Laboratory for Organic Chemistry, ETH Zurich
AUTHORS: K Barylyuk, V Frankevich, AJ Ibáñez, PML Sinues, R ZenobiJOURNAL INFO: CHIMIA International Journal for Chemistry 68 (3), 119-123YEAR: 2014LINK...
Real-Time Analysis of Trace Ambient Vapors by Secondary Electrospray Ionization-Mass Spectrometry
AUTHORS: P SinuesJOURNAL INFO: ETH ZurichYEAR: 2014LINK https://www.research-collection.ethz.ch/handle/20.500.11850/210783
Gesellschaftsnachrichten/Informations de la Société
AUTHORS: A van Breda, JT Annema, MB von Bartheld, SM Choi, J Lee, YS Park, ...JOURNAL INFO: Respiration 87 (4), 352-352YEAR: 2014LINK...
Real-time detection of chemical warfare agent simulants in forensic samples using active capillary plasma ionization with benchtop and field-deployable mass spectrometers
AUTHORS: M Dumlao, PML Sinues, M Nudnova, R ZenobiJOURNAL INFO: Analytical Methods 6 (11), 3604-3609YEAR: 2014LINK https://pubs.rsc.org/en/content/articlehtml/2014/ay/c4ay00303a
Breath analysis in real time by mass spectrometry in chronic obstructive pulmonary disease
AUTHORS: PML Sinues, L Meier, C Berchtold, M Ivanov, N Sievi, G Camen, M Kohler, ...JOURNAL INFO: Respiration 87 (4), 301-310YEAR: 2014LINK https://www.karger.com/Article/FullText/357785
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